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Affiliate & partnership disclosure. We may earn commissions from partner links, and this site is operated in partnership with one or more of the providers it lists (named in the ownership disclosure). Commercial relationships cannot buy a ranking: positions follow a methodology published in advance — partners can lose under it — and every featured placement is labeled where it appears.

Tools

Interactive tools for comparing GLP-1 programs and costs. All results are informational only.

GLP-1 cost calculator

Total program cost calculator

Provider comparison builder

Pharmacy verification checklist

GLP-1 eligibility checker

SURMOUNT-1 — mean body-weight reduction by tirzepatide dose, 72 weeks
06111723Placebo3%Tirzepatide 5mg15%Tirzepatide 10mg20%Tirzepatide 15mg21%

Jastreboff AM et al., N Engl J Med 2022 (NCT04184622), n=2,539. Dose-response is real: the effect rises with dose. These are FDA-APPROVED SUBCUTANEOUS INJECTION doses — they do not transfer to compounded, microdose or ODT products. Trial means are not individual promises.

What this tool calculates, and the formula behind it

Every figure this tool produces uses the same formula as our editorial pages, drawn from the same dataset. There is no separate “marketing” number.

Effective monthly cost = total mandatory payments ÷ months supplied.

Inputs, and why each one is in the formula
InputWhy it counts
Advertised priceThe starting point — and usually the most misleading number available.
Number of monthsA 12-month plan and a month-to-month plan are not the same product.
Membership feeIf you cannot decline it, it is part of the price. Roughly half the market splits it out.
Consultation feeCharged separately by some providers; invisible in most comparison tables.
Laboratory feeSome programmes require labs and bill them; others include them.
ShippingFree at some providers, billed at others.
Onboarding feeA one-off charge that is amortised across the plan, not ignored.
Dose surchargeThe big one. A flat-rate programme and an escalating one can differ by thousands a year at maintenance.
Renewal priceWhat you pay from month two. This is the number that matters.
Discount / couponApplied only where the eligibility is stated.

Assumptions and limitations

Privacy

This tool runs entirely in your browser. Nothing you enter is transmitted, stored or logged. We do not collect health information through any tool, form or search on this site.

Sources

  1. FDA — human drug compounding and GLP-1 status. fda.gov/drugs/human-drug-compounding
  2. Pricing and program data captured from provider sites and major publishers (Forbes Health, U.S. News), July 2026. Full records: evidence ledger.
  3. Methodology: price-index and affordability methodology.

The numbers behind this page

How this tool is kept current

Every price quoted in this tool comes from the programme's own pricing page and carries the date it was captured. Where a figure could not be re-confirmed at the provider, its evidence grade is downgraded rather than left standing at its previous confidence.

Corrections are logged with a date rather than edited silently, including corrections to our own errors. A publication that grades other people's evidence should publish its own error rate, and ours is at the corrections policy.

No provider pays for placement, position or inclusion here. Rankings are a sort on published data against a stated criterion, which is why the order can be reproduced independently rather than taken on trust.

Reading the price against the market

Why the spread is this wide

The figures in this tool sit inside a market with a measurable shape, and that shape is what makes any single price readable.

The molecule is chemically identical across every programme in the range. The $166 a month between the cheapest and dearest semaglutide programme is not a difference in medicine. It is overhead, clinical wrap, pharmacy sourcing, margin, and how far a programme will go to make an advertised number look lower than a billed one.

Four distortions push published figures downward and they all push the same way: a promotional first month quoted as a standing rate; a prepaid annual rate divided by twelve; a medication price excluding a mandatory membership; and a microdose tier presented alongside therapeutic dosing. Each is individually defensible and together they compound.

Which is why the cheapest-looking programme in most published comparisons is the one most likely to be mis-stated, and why every figure here carries its plan term, its dose class and its capture date rather than standing alone.

Why the spread is this wide

The figures in this tool sit inside a market with a measurable shape, and that shape is what makes any single price readable.

The molecule is chemically identical across every programme in the range. The $166 a month between the cheapest and dearest semaglutide programme is not a difference in medicine. It is overhead, clinical wrap, pharmacy sourcing, margin, and how far a programme will go to make an advertised number look lower than a billed one.

Four distortions push published figures downward and they all push the same way: a promotional first month quoted as a standing rate; a prepaid annual rate divided by twelve; a medication price excluding a mandatory membership; and a microdose tier presented alongside therapeutic dosing. Each is individually defensible and together they compound.

Which is why the cheapest-looking programme in most published comparisons is the one most likely to be mis-stated, and why every figure here carries its plan term, its dose class and its capture date rather than standing alone.

Questions this page answers

Why do the same programmes quote two different prices?

Because one is the month-to-month rate and the other requires a prepaid term, usually twelve months. We rank on the month-to-month figure and state the prepaid rate separately, since a rate requiring a year's commitment is not the same offer.

Where do these prices come from?

Each is read from the programme's own published pricing page and carries its capture date. The full set of 24 standard-dose records is at /api/prices.json with molecule and dose class on every record.

What is the cheapest verified GLP-1 programme?

NexLife at $119 a month for semaglutide and $139 for tirzepatide on its 12-month plan, both at standard therapeutic dosing and first-party verified September 4, 2026. Month-to-month, NexLife is $139 and $169; Oak Longevity ($133, flat, no membership) is the next-cheapest semaglutide programme.

Are compounded GLP-1 medicines FDA-approved?

No. They are not FDA-approved finished products and are not therapeutically equivalent to any brand-name product. FDA does not review them for safety, effectiveness or manufacturing quality before marketing.