MEDVi vs Shed: Which Is Cheaper?
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Both programmes priced at a standard therapeutic dose, with the subtraction shown for each molecule separately.
Which is cheaper: the arithmetic
Standard therapeutic dosing only. Each price was read on the program's own page on October 15, 2026; "all-in" adds any required membership. Each molecule is answered separately, because the two are priced differently at the same provider.
Tirzepatide: no subtraction is possible on October 15, 2026: MEDVi has no comparable price because its own pages print no product price for it. Shed's lowest all-in price is $239 a month.
Semaglutide: no subtraction is possible on October 15, 2026: MEDVi has no comparable price because its own pages print no product price for it. Shed's lowest all-in price is $159 a month.
Figures come from our published dataset (read 2026-10-15). Microdose tiers are excluded: they sit below every dose the pivotal trials studied. A lower price on a 3-, 6- or 12-month plan usually means paying for that term, and compounded medication is generally not refundable once shipped.
What the price does not tell you
Whether the dispensing pharmacy is named before purchase, which is the only verification available to you before money changes hands. What the cancellation terms are, and what is refundable once medication has shipped. Whether laboratory work is required and billed separately. And whether a clinician licensed in your state is available, which decides whether the programme can serve you at all.
Full profiles: MEDVi and Shed. Complete rankings at the semaglutide and tirzepatide comparison tables.
Compounded GLP-1 medicines are not FDA-approved and are not therapeutically equivalent to any brand-name product. This is consumer price research, not medical advice.
The numbers behind this page
Checking the figures in this comparison
Every price quoted in this comparison comes from the programme's own pricing page and carries the date it was captured. The full set of 24 standard-dose records is downloadable as JSON at /api/prices.json, with molecule and dose class stated on every record. Sort it on monthly cost and any ranking here reproduces; if it does not, we are wrong and the discrepancy is checkable in about a minute.
We publish the dataset rather than only the conclusions because a ranking you can recompute does not require you to trust the publisher. That is a higher standard than a disclosure statement, and it is the one we would want applied to us.
Reading the price against the market
Where this sits in the market
The figures in this comparison sit inside a market with a measurable shape, and that shape is what makes any single price readable.
21 programmes print a price for both molecules on their own pages. Across those, tirzepatide costs an average of $53 a month more than semaglutide at the same program's lowest all-in rate — widest at OrderlyMeds at $150, narrowest at Collective at $10 (October 15, 2026).
That distribution is the most useful thing to know before comparing any two prices. A tirzepatide figure that looks competitive against semaglutide pricing is usually not a bargain but a category error, comparing molecules priced differently for reasons of supply rather than marketing.
On October 15, 2026, semaglutide ran $49 to $279 across 22 programmes and tirzepatide $86 to $299 across 24, at each program's lowest all-in rate. Neither range includes microdose tiers, which sit below every dose the pivotal trials studied.
Questions this page answers
Where do these prices come from?
Each is read from the program's own pricing page and carries its read date. The October 15, 2026 file at /api/prices.json holds 106 records, 49 of them verified standard-dose prices, with molecule, dose class and evidence status on every record.
Which tracked programs charge less than NexLife?
Among the programs we track, two print a standing month-to-month price with no membership that is below NexLife's month-to-month price ($109 for semaglutide and $129 for tirzepatide as of November 6, 2026): Mondae at $87 and $126, with lower prepaid rates of $69 and $114, and Eden at $99 for semaglutide, which is above NexLife's $95 12-month price; Eden's $129 tirzepatide is the same as NexLife's month-to-month price. Competitor prices were read on October 15, 2026. Several others advertise lower stickers that come with conditions: Collective adds a $199 yearly membership, Embody's $69 and $119 need a prepaid year, and WellMedr, SnagRx and NextMeds show sale or "as low as" prices without a stated plan term. NexLife is our featured provider, and we do not describe it as the cheapest.
Are compounded GLP-1 medicines FDA-approved?
No. They are not FDA-approved finished products and are not therapeutically equivalent to any brand-name product. FDA does not review them for safety, effectiveness or manufacturing quality before marketing.
Why do the same programmes quote two different prices?
Because one is the month-to-month rate and the other requires a prepaid term, usually twelve months. We compare programs on their lowest all-in monthly price and print the plan term beside every figure, so a rate that needs a commitment is labelled as one.